What Makes iATRO Different

At iATRO, we take an effects-based targeting approach to wellness — designing every formula to align with the body’s natural systems and activate balance through synergy, not isolation. Our formulations are built around the entourage effect, the principle that cannabinoids, mushrooms, and botanicals perform best when they work together. This layered, multi-system design allows each ingredient to enhance the others’ function, creating results you can feel — from sharper focus to deeper rest.

Guided by both modern research and advanced AI formulation modeling, each iATRO blend is engineered toward a clearly defined outcome — calm, clarity, energy, focus, or rest. By analyzing natural compound interactions through intelligent data modeling, we’re able to identify synergistic pairings that amplify performance and bioavailability, ensuring that every formula delivers targeted, measurable effects rooted in natural harmony.

The Three Pillars of iATRO Formulation

Every iATRO formula is built from three synergistic systems that work together to support balance, focus, and restoration.
Each layer plays a distinct role within our effects-based targeting approach — cannabinoids regulate, mushrooms adapt, and nutrients refine.
Together, they form a complete network of wellness designed for results you can feel.

Cannabinoids
The Foundation of Balance

Cannabinoids interact with the body’s endocannabinoid system to stabilize mood, reduce stress, and promote equilibrium. They set the baseline that allows the rest of the formula to perform in harmony.

Functional Mushrooms
The Adaptive Layer

Mushrooms bring resilience to the system — helping the body respond to stress, maintain energy, and sharpen mental focus. These adaptogens build stability from the inside out, amplifying the performance of cannabinoids and nutrients alike.

Vitamins & Nutraceuticals
The Precision Layer

This layer provides the fine-tuning. Nutrients like Magnesium Glycinate, Vitamin B12, and L-Theanine optimize energy metabolism, focus, and calm. Each is carefully selected for purity and bioavailability, ensuring consistent, measurable results.

Adaptogens, Nootropics & Micronutrients

In wellness science, terms like adaptogen and nootropic describe how different ingredients interact with the body and mind. While they often overlap, each offers a distinct perspective on how balance and performance are achieved.

Adaptogens help the body manage stress and maintain equilibrium. Mushrooms such as Reishi, Maitake, and Cordyceps fit this category, long associated with resilience, stamina, and the ability to restore internal balance.

Nootropics enhance clarity, focus, and cognitive endurance. Lion’s Mane leads this group, while nutrients like Vitamin B12 and L-Theanine support sustained attention and mental calm without overstimulation.

Micronutrients & Botanicals round out each formula with gentle, grounding support. Compounds like Magnesium Glycinate, Valerian Root, and Zinc strengthen foundational wellness — promoting relaxation, recovery, and stability in daily rhythm.

How it works:
iATRO formulas layer adaptogens for balance, nootropics for clarity, and botanicals for reinforcement. It’s this structured synergy — ancient tradition refined through modern science — that creates a complete, targeted wellness experience.

At iATRO, every gummy is built with intention. We combine time-honored ingredients with modern insights to create blends that feel natural, balanced, and aligned with everyday life. Below, you’ll find the core ingredients that appear across our formulations. Each has a history rooted in traditional use and a purposeful role in how our gummies are designed to feel. Our focus is on experience, balance, and quality—helping you see how each ingredient contributes to the unique character of every iATRO blend.

Ingredient Library: History, Roles, and Why We Use Them

Cannabinoids

Delta-9 THC – The Cornerstone

DΔ9-THC is the cannabinoid most recognized for its interaction with the body’s endocannabinoid system. It binds primarily to CB1 and CB2 receptors, influencing pathways related to mood, perception, and stress regulation. Research indicates that, at precise low levels, Δ9-THC helps support mood balance, cognitive coordination, and a healthy stress response through its modulation of neurotransmitter and endocannabinoid signaling (Russo & Marcu, British Journal of Pharmacology, 2017; Citti et al., Journal of Pharmaceutical and Biomedical Analysis, 2018). In all iATRO blends, Delta-9 THC functions as a key component of the entourage effect—enhancing the overall harmony and effectiveness of each formulation.

CBD (Cannabidiol) – The Stabilizer

CBD is the cannabinoid most closely associated with balance and restoration. It interacts widely across the endocannabinoid, serotonin, and GABA receptor systems—key networks that influence mood, stress resilience, and overall equilibrium. Research indicates that CBD helps regulate neurotransmitter activity, promoting calm focus, emotional steadiness, and a healthy stress response (Blessing et al., Neurotherapeutics, 2015; Millar et al., Frontiers in Pharmacology, 2018). In iATRO’s Meditate, Active, and Perfect blends, CBD forms the stabilizing foundation—grounding each formula in composure and clarity while supporting the body’s ability to adapt smoothly to both rest and activity.

CBG (Cannabigerol) – The Clear-Minded One

CBG is often called the “focus cannabinoid.” It engages both the endocannabinoid and adrenergic systems, influencing key neurotransmitters involved in alertness, mood regulation, and motivation. Research indicates that CBG helps support cognitive clarity and composure by modulating GABA and serotonin activity while promoting a balanced inflammatory response (Brierley et al., Biochemical Pharmacology, 2016). In iATRO’s Perfect and Focus blends, CBG sharpens attention and steadiness—enhancing concentration, sustaining mental energy, and helping the body remain calm, centered, and fully engaged.

CBC (Cannabichromene) – The Uplifter

CBC is one of cannabis’ “quiet cannabinoids.” Often overshadowed by THC and CBD, it plays a distinct role in promoting balance and mental clarity. Though it doesn’t bind strongly to CB1 receptors, CBC interacts with multiple biological pathways that influence mood, perception, and homeostasis. Research indicates that CBC can modulate key processes linked to inflammation, influencing endocannabinoid signaling and helping the body maintain internal equilibrium (DeLong et al., British Journal of Pharmacology, 2010). In iATRO’s Focus and Perfect blends, CBC provides a grounding counterpoint to CBG’s clarity—enhancing composure and sustaining an even, uplifted tone throughout the experience.

CBN (Cannabinol) – The Gentle Companion

CBN is often called the “rest cannabinoid.” Formed naturally as THC matures, it delivers a calm, stabilizing effect distinct from other cannabinoids. Rather than binding strongly to CB1 receptors, CBN engages multiple biological pathways that help regulate the body’s transition into restorative states. Research indicates it influences endocannabinoid and sensory signaling involved in relaxation, tension relief, and nighttime balance (Russo & Marcu, British Journal of Pharmacology, 2017). In iATRO’s Sleep blend, CBN provides the foundation for a deep sense of calm—quieting mental activity and preparing the body for restorative rest when paired with L-theanine and Reishi.

THCv (Tetrahydrocannabivarin) – The Drive Cannabinoid

THCV is often referred to as the “clarity cannabinoid.” Structurally related to THC but functionally distinct, it interacts with CB1 and CB2 receptors to influence energy metabolism and appetite signaling. Research suggests that THCV helps support metabolic balance, steady energy, and healthy appetite regulation through its modulation of endocannabinoid and dopamine pathways (Wargent et al., British Journal of Pharmacology, 2013; Riedel et al., Diabetes Care, 2012). In iATRO’s Active blend, THCV refines focus and motivation—helping sustain alertness, promote metabolic efficiency, and maintain an energized yet even-keeled state throughout the day.

The Power of Functional Mushrooms

Functional mushrooms play a vital role in helping the body adapt, recover, and perform. Long used in traditional medicine, they support balance across mood, focus, and energy — building resilience from within. In iATRO formulations, mushrooms serve as the adaptive core within our effects-based targeting system. They work in harmony with cannabinoids and nutraceuticals to help the body regulate stress, maintain stability, and restore equilibrium naturally. These powerful adaptogens strengthen the body’s response to daily demands, creating calm when it’s needed and clarity when it’s called for — the essence of balance at the heart of every iATRO formula.

Known in East Asia as the “mushroom of immortality,” Reishi has been used for thousands of years in teas, tonics, and rituals tied to balance and longevity. Traditionally, it was believed to bring harmony to both body and mind. Today, it’s often associated with stress relief, calm, and immune support.

In iATRO blends, Reishi plays a central role in our Sleep and Meditate gummies. It helps create a soothing foundation that quiets mental chatter and promotes a sense of inner balance. Paired with cannabinoids like CBN or CBD, Reishi enhances the feeling of winding down, making it easier to let go of the day and find restorative rest..

Reishi – The Grounding Mushroom

First discovered in the high mountains of Tibet and China, Cordyceps was treasured by herders and monks who noticed its connection to stamina, endurance, and vitality. Historically rare and highly prized, it was often used to promote resilience in demanding environments.

Today, Cordyceps is valued for the way it supports oxygen use and energy metabolism, making it a favorite in fitness and performance circles. In iATRO, Cordyceps is found in our Active and Meditate gummies, where it provides smooth, steady energy without overstimulation. It’s perfect for workouts, busy days, or simply keeping a calm, alert mindset.

Cordyceps – The Energy Mushroom

Lion’s Mane has long been used in East Asia, not just for nourishment but also as a revered aid for focus and concentration. Its delicate, shaggy appearance earned it a place in both traditional medicine and cuisine, and in modern wellness it’s widely discussed for its potential to support cognitive health.

We use Lion’s Mane in Focus and Perfect gummies, where clarity matters most. It helps you feel sharp, and mentally present without the jitters of caffeine. Whether you’re deep in work, studying, or just trying to stay on task, Lion’s Mane creates the foundation for clear, sustainable focus.

Lion’s Mane – The Clarity Mushroom

Maitake – The Balance Mushroom

Maitake, or “dancing mushroom,” earned its name in Japan from the joy people felt upon discovering it. Traditionally, it was linked to vitality, resilience, and balance, often consumed to fortify the body during stressful times.

Modern wellness circles see Maitake as a stabilizer — a mushroom that complements energy blends by smoothing out highs and lows. In iATRO’s Active and Perfect formulas, Maitake rounds out the profile so you feel energized yet steady, uplifted without becoming restless. It’s the quiet anchor that helps your body handle both movement and focus with ease.

Turkey Tail is one of the most recognizable mushrooms in nature, with its colorful, fan-like layers. Across Asia, Europe, and the Americas, it has been steeped in teas and tonics for centuries, always connected to broad-spectrum wellness.

Today, it’s widely appreciated for its versatility and the way it strengthens a daily wellness routine. In iATRO blends like Focus and Perfect, Turkey Tail expands the foundation of the formula, offering an extra layer of support. It doesn’t create an immediate sensation on its own, but instead ensures the entire blend feels more rounded, steady, and reliable day after day.

Turkey Tail – The Wellness Mushroom

Nutraceuticals & Botanicals

While cannabinoids and mushrooms form the backbone of iATRO, our blends are rounded out with a careful selection of nutraceuticals and botanicals. These are the everyday nutrients and plant-based helpers that give each gummy its finishing touch — adding smoothness, balance, and familiarity. Together, they ensure our formulas feel intentional, approachable, and complete.

Naturally found in green and black tea, L-Theanine has been sipped for centuries as part of daily rituals that promote calm focus. Tea ceremonies across Asia often centered around its quieting yet clear-minded qualities.

We use L-Theanine as a gentle calm enhancer. It doesn’t sedate — instead, it softens edges, smooths out intensity, and creates a sense of calm alertness. It’s equally at home in our Focus gummies for steady engagement, or in Sleep for a peaceful wind-down.

L-Theanine – Calm from Tea

Magnesium (as Glycinate) – The Relaxation Mineral

Unlike other forms that can cause digestive discomfort or deliver uneven results, magnesium glycinate is efficiently absorbed, supporting relaxation, stress resilience, and restorative sleep without disruption.
It’s a more refined, more expensive ingredient — chosen because precision matters. In iATRO’s Sleep and Meditate blends, magnesium glycinate helps smooth the transition between activity and rest, reinforcing the body’s natural rhythm of recovery and calm. When paired with cannabinoids like CBN and adaptogenic mushrooms such as Reishi, it deepens the restorative experience, helping the body unwind fully and wake renewed.

Valerian Root – The Nighttime Herb

Valerian Root has a long history of use as a gentle botanical for relaxation and stress relief. Modern studies link its calming effects to the way it supports GABA activity — helping ease tension, settle the nervous system, and promote a sense of grounded calm.
Unlike synthetic alternatives, Valerian works subtly and naturally, reducing overstimulation without causing drowsiness.

In iATRO formulations, Valerian Root appears in our Meditate blend, where it deepens the sense of calm and helps the body shift out of stress mode. Paired with CBD and Reishi, it enhances relaxation and supports mental clarity, making it an essential element for restoring balance and promoting emotional reset.

Vitamin B12 (Cobalamin) – The Energy Vitamin

Vitamin B12 is essential for energy production, nervous system health, and cognitive performance. iATRO uses methylcobalamin, the methylated and biologically active form of B12 that the body can use immediately. This form is critical because as much as 40% of the population carries a variation in the MTHFR gene, which reduces the body’s ability to convert standard B12 (cyanocobalamin) into its active form. When conversion is limited, energy levels, mood balance, and mental clarity can all be affected.

By using methylated B12, iATRO ensures that this key nutrient is fully available and effective for everyone — regardless of genetic factors. In our Focus, Perfect, and Active blends, methylcobalamin works alongside CBG and Lion’s Mane to support clean energy, sustained focus, and neurological resilience. It’s a precise, higher-quality ingredient that reflects our commitment to both inclusivity and performance — because optimal function shouldn’t depend on genetic luck.

Zinc – The Trace Mineral for Activity

Zinc is a trace mineral essential for immune health, energy metabolism, and cognitive performance. It supports over 300 enzymatic reactions that influence focus, endurance, and recovery — functions that can be depleted under physical or mental stress. Even mild deficiencies can affect alertness and overall vitality.

In iATRO’s Active blend, zinc works alongside Vitamin B12 and Cordyceps to sustain steady energy and support mental stamina throughout the day. It reinforces cellular repair and nutrient metabolism, helping the body perform efficiently without overstimulation. This bioavailable form was selected for its stability and consistency, contributing to the clean, balanced energy that defines the Active experience.

Vitamin C + Vitamin D3 – Everyday Essentials

Vitamins C and D3 form the foundation of immune and metabolic support within iATRO’s Perfect blend. Together, they strengthen cellular defense, promote balanced mood, and sustain daily vitality. Vitamin C supports collagen production and antioxidant protection, while Vitamin D3 regulates immune response and helps maintain steady energy and mental clarity.

In combination with Zinc and adaptogenic mushrooms, these vitamins reinforce the body’s resilience under stress and contribute to a sense of overall balance. This pairing reflects iATRO’s effects-based approach — nutrients selected not for trend, but for precision, harmony, and results you can feel every day.

Folate is a B-vitamin essential for energy metabolism, cellular renewal, and neurotransmitter balance. It supports DNA synthesis, red blood cell production, and overall cognitive function — all critical for maintaining long-term wellness.

iATRO uses methylated folate (L-5-MTHF), the active form the body can use immediately. This is especially important because up to 40% of people carry a variation in the MTHFR gene that limits their ability to convert standard folic acid into its usable form.

In iATRO’s Perfect blend, methylated folate works alongside Vitamin B12, Vitamin C, and Vitamin D3 to support energy, mood stability, and immune balance. It provides clean, consistent support for both mind and body — a foundational ingredient chosen for precision, inclusivity, and real performance.